2021 / present
Publications
Metal-Free and Scalable Sulfoxide Reduction Through the Couple (COCl)2/Et3SiH: Synthesis of Albendazole Hydrochloride
C. Morales-Manrique, S. Gutierrez-Acevedo, L. Adarve-cardona, A. Garay-Talero and D. Gamba-Sánchez*, Synthesis 2025, XXX, DOI: 10.1055/a-2589-4908
Regioselective Organocatalyzed Monochlorination of Arenes with Electrophilic Chlorosulfoniums
A. Garay-Talero, P. Acosta-Guzmán and D. Gamba-Sánchez*, Adv. Synth. Catal. 2023, 365, 4576-4582, DOI: 10.1002/adsc.202300971
Contemporary Approaches for Amide Bond Formation
P. Acosta-Guzmán, A. Ojeda-Porras and D. Gamba-Sánchez*, Adv. Synth. Catal. 2023, 365, 4359-4391. DOI:10.1002/adsc.202301018
An aza-Robinson Annulation Strategy for the Synthesis of Fused Bicyclic Amides: Synthesis of (±)-Coniceine and Quinolizidine
A. Garay-Talero, T. A. C. Goulart, R. D. C. Gallo, R. do C. Pinheiro, C. Hoyos-Orozco, I. D. Jurberg* and D. Gamba-Sánchez* Org. Lett. 2023, 25, 7940-7945, DOI: 10.1021/acs.orglett.3c02798
On the way to potential antifungal compounds: synthesis and in vitro activity of 2-benzofuranylacetic acid amides.
C. Mahecha-Mahecha, P. Borrego-Muñoz, L.M. Pombo and D. Gamba-Sánchez* RSC Adv. 2023, 13, 25296-25304, DOI: 10.1039/D3RA04737G
Ammonia surrogates in the synthesis of primary amines
J. Urbiña-Alvarez, S. Rincón-Carvajal, and D. Gamba-Sánchez* Org. Biomol. Chem. 2023, 21, 7036-7051, DOI:10.1039/D3OB01202F.
One-Pot Synthesis of Dioxime Oxalates
L. Adarve-Cardona, David Ezenarro-Salcedo, Mario A. Macias and D. Gamba-Sánchez* Molbank. 2022, 4, M1473., 10.3390/M1473
Cyclization Strategies Using Imide Derivatives for the Synthesis of Polycyclic Nitrogen-Containing Compounds
Y. Quevedo-Acosta, Igor D. Jurberg* and D. Gamba-Sánchez* Eur J. Org. Chem. 2022, 20222, e202200432.,10.1002/ejoc.202200432
Review, Invited submission for the special collection "Organic and Supramolecular Chemistry in Latin America" selected Cover Feature
Reduction of Sulfoxides in Multigram Scale, an Alternative to the Use of Chlorinated Solvents
L. Adarve-Cardona, and D. Gamba-Sánchez* Processes. 2022, 10, 115., 10.3390/pr10061115
Part of the Special Issue "A Glimpse into Green Chemistry Practices in Academic Laboratories and the Pharmaceutical Industry" Guest Editor, Dr. Diego Gamba Sánchez
Paracetamol Synthesis for Active Learning of Amide Functional Groups in Undergraduate Chemistry Laboratories
F. Garzón-Posse, Y. Quevedo-Acosta, and D. Gamba-Sánchez* J. Chem. Educ. 2022, 99, 2385-2391., 10.1021/acs.jchemed.2c00080
2011 / 2020
Publications
Sequential Suzuki-Miyaura Coupling / Lewis Acid Catalyzed Cyclization: An Entry to Functionalized Cycloalkane-Fused Naphthalenes
C. Mahecha-Mahecha, F. Lecornué*, S. Akinari, T. Charote, T. Ohwada D. Gamba-Sánchez and S. Thibaudeau* Org. Lett. 2020, 22, 6267-6271., 10.1021/acs.orglett.0c02020
Electrophilic Chlorine from Chlorosulfonium Salts: A Highly Chemoselective Reduction of Sulfoxides
P. Acosta-Guzmán, C. Mahecha-Mahecha and D. Gamba-Sánchez* Chem. Eur. J. 2020, 26, 10348-10354., DOI: 10.1002/chem.202001815
An alternative approach to the synthesis of the three fragments of anachelin H
F. Garzón-Posse, J. Prunet, and D. Gamba-Sánchez* Org. Biomol. Chem. 2020, 18, 2702-2715., DOI: 10.1039/D0OB00315H
This article is part of the themed collections: Celebrating Latin American Talent in Chemistry and Total synthesis in OBC
Pummerer Synthesis of Chromanes Reveals a Competition between Cyclization and Reductive Chlorination
P. Acosta-Guzmán, A. Rodríguez-López, and D. Gamba-Sánchez* Org. Lett. 2019, 21, 6903-6908., DOI: 10.1021/acs.orglett.9b02520
Selected for the Virtual Issue Celebrating Chemistry in Latin America of Org. Lett.; J. Org. Chem.; Organometallics
Water-Compatible Synthesis of 2-trifluoromethyl-1,3-dioxanes
L. Becerra-Figueroa, A. Thiniakos, J. Prunet and D. Gamba-Sánchez* Eur. J. Org. Chem. 2018, 48, 6929-6932., DOI: 10.1002/ejoc.201801367
Synthesis of 1,3-Diols by O-Nucleophile Additions to Activated Alkenes
D. Gamba-Sánchez* and J. Prunet* Synthesis. 2018, 50, 3997-4007., DOI: 10.1055/s-0037-1610248
Direct Transamidation Reactions: Mechanism and Recent Advances
P. Acosta-Guzmán, A. Mateus-Gómez and D. Gamba-Sánchez* Molecules. 2018, 23, 2382., DOI: 10.3390/molecules23092382 Wrote by Invitation.
Whole Cells as Biocatalysts in Organic Transformations
F. Garzón-Posse, L. Becerra-Figueroa, J- Hernández-Arias and D. Gamba-Sánchez* Molecules. 2018, 23, 1265., DOI: 10.3390/molecules23061265
An Intramolecular oxa-Michael Reaction on α,β-unsaturated α-amino-δ-hydroxycarboxylic acid esters. Synthesis of Functionlized 1,3-dioxanes
L. Becerra-Figueroa, S. Movilla, J. Prunet, G. P. Miscione* and D. Gamba-Sánchez* Org. Biomol. Chem. 2018, 16, 1277-1286., DOI: 10.1039/c7ob03066e
Diastereoselective Synthesis of Trifluoromethylated 1,3-Dioxanes by Intramolecular oxa-Michael Reaction
L. Becerra-Figueroa, E. Brun, M. Mathieson, L. Farrugia, C. Wilson, J. Prunet*, and D. Gamba-Sánchez* Org. Biomol. Chem. 2017, 15, 301-305., DOI: 10.1039/c6ob02333a
Recent Developments in Amide Synthesis Using Nonactivated Starting Materials
A. Ojeda-Porras, and D. Gamba-Sánchez* J. Org. Chem. 2016, 81, 11548-11555., DOI: 10.1021/acs.joc.6b02358
Insights into the Pummerer Synthesis of Oxaxolines
L. Becerra-Cely, J. Rueda-Espinosa, A. Ojeda-Porras and D. Gamba-Sánchez* Org. Biomol. Chem. 2016, 14, 8474-8485., DOI: 10.1039/c6ob01666a
Transamidation of Thioacetamide Catalyzed by SbCl3
A. Ojeda-Porras, and D. Gamba-Sánchez* Tetrahedron. Lett. 2015, 56, 4308-4311., DOI: 10.1016/j.tetlet.2015.05.067
Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support
A. Ojeda-Porras, A. Hernandez-Santana, and D. Gamba-Sánchez* Green Chem. 2015, 17, 3157-3163., DOI: 10.1039/C5GC00189G
Transamidation of Carboxamides Catalyzed by Fe(III) and Water
L. Becerra-Figueroa, A. Ojeda-Porras, and D. Gamba-Sánchez* J. Org. Chem. 2014, 79, 4544-4552., DOI: 10.1021/jo500562w
Fumagillin and structurally related molecules as source of new drugs.
D. Gamba-Sánchez* Mini Rev. Org. Chem. 2012, 9, 126-142., DOI: 10.2174/157019312800604724
Book Chapters
Paola Acosta-Guzmán, John Corredor-Barinas andDiego Gamba-Sánchez* Amide Bond Activation, Ed. M. Szostak. Wiley and Sons, 2022, CH: 6, pp 187-219 ISBN: 978-3-527-34831-2.
Camilo Mahecha-Machecha, Laura Adarve-Cardona and Diego Gamba-Sánchez* . Targets in Heterocyclic Chemistry Systems-Chemistry and Properties (THS), Ed. O. Attanasi and G. Bartolo. Societá Chimica Italiana, 2020, vol. 24, Chapter:9
Paola Acosta-Guzmán and Diego Gamba-Sánchez* . Greener Synthesis of Organic compounds, Ed. A. Nag. CRC Press, Taylor and Francis Group, Boca Raton FL, US, 2022, CH 3, ISBN: 978-0-367-54408-9
Andrea Ojeda-Porras and Diego Gamba-Sánchez* . Greener Synthesis of Organic compounds, Ed. A. Nag. CRC Press, Taylor and Francis Group,Boca Raton FL, US, 2022, CH 2, ISBN: 978-0-367-54408-9
Diego Gamba-Sánchez* and Fabián Garzón-Posse. Molecular Rearrangements in Organic Synthesis, Ed. C. Rojas. Wiley, 2015, CH 20, pp. 661-702., ISBN: 978-1-118-34796-6
2008 / 2010
From Post-Doc, Ph.D and Master
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- Hydrogen Peroxide: A versatile reagent in organic synthesis.
Diego Gamba-Sánchez.
Synlett, 2008, 1101-1102
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[2+2]-Photocycloaddition Reactions of Tetronic Acid Esters and Amides.
Jörg P. Hehn, Diego Gamba-Sánchez, Michael Kemmler, Martin Fleck, Birte Basler, Thorsten Bach.
Synthesis, 2010, 2308-2312.
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Synthesis of Modified Methyl Furanosides by Intramolecular oxa-Michael Reaction Followed by Pummerer Rearrangement.
Diego Gamba-Sanchez and Joëlle Prunet.
J.Org. Chem. 75, 2010, 3129-3132.
DOI: 10.1021/jo100241e
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Regio- and diastereoselective addition of allylic thioethers to aldehydes.
Diego Gamba-Sanchez, Raphaël Oriez, Joëlle Prunet.
Tetrahedron Lett., 50, 8, 2009, 883-885.
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Cyclisation/fluorination of nitrogen containing dienes in superacid HF–SbF5: a new route to 3- and 4-fluoropiperidines.
Emilie Vardelle, Diego Gamba-Sanchez, Agnès Martin-Mingot, Marie-Paule Jouannetaud, Sébastien Thibaudeau and Jérôme Marrot.
Chem. Commun, 12, 2008, 1473-1475.
DOI: 10.1039/B719309B
- Hydrogen Peroxide: A versatile reagent in organic synthesis.