2021 / present

Publications

Ammonia surrogates in the synthesis of primary amines

J. Urbiña-AlvarezS. Rincón-Carvajal, and  D. Gamba-Sánchez* Org. Biomol. Chem. 2023, X, DOI:10.1039/D3OB01202F.

One-Pot Synthesis of Dioxime Oxalates

L. Adarve-Cardona, David Ezenarro-Salcedo, Mario A. Macias and  D. Gamba-Sánchez* Molbank. 2022, 4, M1473., 10.3390/M1473

Cyclization Strategies Using Imide Derivatives for the Synthesis of Polycyclic Nitrogen-Containing Compounds

Y. Quevedo-Acosta, Igor D. Jurberg* and  D. Gamba-Sánchez* Eur J. Org. Chem. 2022, 20222, e202200432.,10.1002/ejoc.202200432

Review, Invited submission for the special collection "Organic and Supramolecular Chemistry in Latin America" selected Cover Feature

Reduction of Sulfoxides in Multigram Scale, an Alternative to the Use of Chlorinated Solvents

L. Adarve-Cardonaand  D. Gamba-Sánchez* Processes. 2022, 10, 115., 10.3390/pr10061115

Part of the Special Issue "A Glimpse into Green Chemistry Practices in Academic Laboratories and the Pharmaceutical Industry" Guest Editor, Dr. Diego Gamba Sánchez

Paracetamol Synthesis for Active Learning of Amide Functional Groups in Undergraduate Chemistry Laboratories

F. Garzón-Posse, Y. Quevedo-Acostaand  D. Gamba-SánchezJ. Chem. Educ. 2022, 99, 2385-2391., 10.1021/acs.jchemed.2c00080


2011 / 2020 

Publications

Sequential Suzuki-Miyaura Coupling / Lewis Acid Catalyzed Cyclization: An Entry to Functionalized Cycloalkane-Fused Naphthalenes

C. Mahecha-Mahecha, F. Lecornué*, S. Akinari, T. Charote, T. Ohwada D. Gamba-Sánchez and S. Thibaudeau* Org. Lett. 2020, 22, 6267-6271., 10.1021/acs.orglett.0c02020

Electrophilic Chlorine from Chlorosulfonium Salts: A Highly Chemoselective Reduction of Sulfoxides

P. Acosta-Guzmán, C. Mahecha-Mahecha and D. Gamba-Sánchez* Chem. Eur. J. 202026, 10348-10354., DOI: 10.1002/chem.202001815

An alternative approach to the synthesis of the three fragments of anachelin H

F. Garzón-Posse, J. Prunet, and D. Gamba-Sánchez* Org. Biomol. Chem. 202018, 2702-2715., DOI: 10.1039/D0OB00315H

This article is part of the themed collections: Celebrating Latin American Talent in Chemistry and Total synthesis in OBC

Pummerer Synthesis of Chromanes Reveals a Competition between Cyclization and Reductive Chlorination

P. Acosta-GuzmánA. Rodríguez-López, and D. Gamba-Sánchez* Org. Lett201921, 6903-6908., DOI: 10.1021/acs.orglett.9b02520

Selected for the Virtual Issue Celebrating Chemistry in Latin America of Org. Lett.; J. Org. Chem.; Organometallics

Water-Compatible Synthesis of 2-trifluoromethyl-1,3-dioxanes

L. Becerra-Figueroa, A. Thiniakos, J. Prunet and D. Gamba-Sánchez* Eur. J. Org. Chem201848, 6929-6932., DOI: 10.1002/ejoc.201801367

Synthesis of 1,3-Diols by O-Nucleophile Additions to Activated Alkenes

D. Gamba-Sánchez* and J. Prunet* Synthesis201850, 3997-4007., DOI: 10.1055/s-0037-1610248

Direct Transamidation Reactions: Mechanism and Recent Advances

P. Acosta-Guzmán, A. Mateus-Gómez and D. Gamba-Sánchez* Molecules201823, 2382., DOI: 10.3390/molecules23092382 Wrote by Invitation.

Whole Cells as Biocatalysts in Organic Transformations

F. Garzón-Posse, L. Becerra-Figueroa, J- Hernández-Arias and D. Gamba-Sánchez* Molecules201823, 1265., DOI: 10.3390/molecules23061265

An Intramolecular oxa-Michael Reaction on α,β-unsaturated α-amino-δ-hydroxycarboxylic acid esters. Synthesis of Functionlized 1,3-dioxanes

L. Becerra-Figueroa, S. Movilla, J. Prunet, G. P. Miscione* and D. Gamba-Sánchez* Org. Biomol. Chem201816, 1277-1286., DOI: 10.1039/c7ob03066e

Diastereoselective Synthesis of Trifluoromethylated 1,3-Dioxanes by Intramolecular oxa-Michael Reaction

L. Becerra-Figueroa, E. Brun, M. Mathieson, L. Farrugia, C. Wilson, J. Prunet*, and D. Gamba-Sánchez* Org. Biomol. Chem2017, 15, 301-305., DOI: 10.1039/c6ob02333a

Recent Developments in Amide Synthesis Using Nonactivated Starting Materials

A. Ojeda-Porras, and D. Gamba-Sánchez* J. Org. Chem201681, 11548-11555., DOI: 10.1021/acs.joc.6b02358

Insights into the Pummerer Synthesis of Oxaxolines

L. Becerra-Cely, J. Rueda-Espinosa, A. Ojeda-Porras and D. Gamba-Sánchez* Org. Biomol. Chem201614, 8474-8485., DOI: 10.1039/c6ob01666a

Transamidation of Thioacetamide Catalyzed by SbCl3

A. Ojeda-Porras, and D. Gamba-Sánchez* Tetrahedron. Lett201556, 4308-4311., DOI: 10.1016/j.tetlet.2015.05.067

Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support

A. Ojeda-Porras, A. Hernandez-Santana, and D. Gamba-Sánchez* Green Chem. 2015, 17, 3157-3163., DOI: 10.1039/C5GC00189G

Transamidation of Carboxamides Catalyzed by Fe(III) and Water

L. Becerra-Figueroa, A. Ojeda-Porras, and D. Gamba-Sánchez* J. Org. Chem201479, 4544-4552., DOI: 10.1021/jo500562w

Fumagillin and structurally related molecules as source of new drugs.

D. Gamba-Sánchez* Mini Rev. Org. Chem. 2012, 9, 126-142., DOI: 10.2174/157019312800604724

Book Chapters

Trasnsamidation of Carboxamides and Amide Derivatives: Mechanistic Insights, Concepts and Reactions

Paola Acosta-Guzmán, John Corredor-Barinas andDiego Gamba-Sánchez*  Amide Bond Activation, Ed. M. Szostak. Wiley and Sons, 2022, CH: 6, pp 187-219 ISBN: 978-3-527-34831-2.

Use of Chlrosulfonium Salts in the Synthesis of Oxygenated Heterocycles

Camilo Mahecha-Machecha, Laura Adarve-Cardona and Diego Gamba-Sánchez* . Targets in Heterocyclic Chemistry Systems-Chemistry and Properties (THS), Ed. O. Attanasi and G. Bartolo. Societá Chimica Italiana, 2020, vol. 24, Chapter:9 

Greener Methods for Halogenation of Aromatic Compounds

Paola Acosta-Guzmán and Diego Gamba-Sánchez* . Greener Synthesis of Organic compounds, Ed. A. Nag. CRC Press, Taylor and Francis Group, Boca Raton FL, US, 2022, CH 3, ISBN: 978-0-367-54408-9

New greener developments in direct amidation of carboxylic acids

Andrea Ojeda-Porras and Diego Gamba-Sánchez* . Greener Synthesis of Organic compounds, Ed. A. Nag. CRC Press, Taylor and Francis Group,Boca Raton FL, US, 2022, CH 2, ISBN: 978-0-367-54408-9

Pummerer-type Reactions as Powerful Tools in Organic Synthesis

Diego Gamba-Sánchez* and Fabián Garzón-Posse. Molecular Rearrangements in Organic Synthesis, Ed. C. Rojas. Wiley, 2015, CH 20, pp. 661-702., ISBN: 978-1-118-34796-6

2008 / 2010 

From Post-Doc, Ph.D and Master

    • Hydrogen Peroxide: A versatile reagent in organic synthesis.

      Diego Gamba-Sánchez.

      Synlett, 2008, 1101-1102

      DOI: 10.1055/s-2008-1066990

    • [2+2]-Photocycloaddition Reactions of Tetronic Acid Esters and Amides.

      Jörg P. Hehn, Diego Gamba-Sánchez, Michael Kemmler, Martin Fleck, Birte Basler, Thorsten Bach.

      Synthesis, 2010, 2308-2312.

      DOI: 10.1055/s-0029-1218793

    • Synthesis of Modified Methyl Furanosides by Intramolecular oxa-Michael Reaction Followed by Pummerer Rearrangement.  

      Diego Gamba-Sanchez and Joëlle Prunet.

      J.Org. Chem. 75, 2010, 3129-3132.

      DOI: 10.1021/jo100241e

    • Regio- and diastereoselective addition of allylic thioethers to aldehydes.

      Diego Gamba-Sanchez, Raphaël Oriez, Joëlle Prunet.

      Tetrahedron Lett., 50, 8, 2009, 883-885.

      DOI: 10.1016/j.tetlet.2008.12.009

    • Cyclisation/fluorination of nitrogen containing dienes in superacid HF–SbF5: a new route to 3- and 4-fluoropiperidines.

      Emilie Vardelle, Diego Gamba-Sanchez, Agnès Martin-Mingot, Marie-Paule Jouannetaud, Sébastien Thibaudeau and Jérôme Marrot.

      Chem. Commun, 12, 2008, 1473-1475.

      DOI: 10.1039/B719309B